Phytomelatonin Rejuvenating Serum

Minimum commitment of 3 delivery cycles. 

35 years of natural skincare research by Dr. Francesca Ferri has culminated in this breakthrough serum with Alpine Plant Melatonin (APM), a patented extract of Phytomelatonin.

This radical step forward in natural skincare has been shown in independent clinical trials to visibly reduce signs of skin ageing. Wrinkle depth, wrinkle volume, brown spots and pore visibility showed significant decreases after just four weeks, while skin elasticity notably increased.

Remarkably, this product can achieve these effects while even calming and soothing the skin. Indeed in the clinical trials, the Phytomelatonin Rejuvenating Serum helped to visibly decrease red areas; and dermatological testing has even approved this serum for sensitive skin.

Suitable for mature, dry or dehydrated skin.

Phytomelatonin Rejuvenating Serum
Phytomelatonin Rejuvenating Serum Bottle
Phytomelatonin Rejuvenating Serum Texture

Product benefits


Clinically proven to reduce wrinkle depth and volume.


Clinically proven to reduce dark spots.  


Clinically proven to reduce pore visibility.


Clinically proven to increase elasticity.


Clinically proven to help reduce red areas.

The result of the

work of a lifetime

From her student days in the 70s, Dr. Francesca Ferri has been fascinated by the hormone melatonin and in particular, its counterpart in plants: Phytomelatonin. Through the development of a patented technique to extract Phytomelatonin from plants in 2006; the publication of research in 2019 that showed Phytomelatonin can regulate skin ageing; and now with the launch of Phytomelatonin Rejuvenating Serum, Dr. Ferri’s fascination has grown into a lifelong quest to understand the role and benefits of Phytomelatonin.

Phytomelatonin rejuvenating serum delivers visibly younger skin at 4 Weeks, even more so at 8 Weeks

The usual signs of skin ageing: wrinkle volume, brown spots, UV spots and visible pores showed significant decreases. While that feature of younger skin, elasticity, actually increased.

Strong in Effect But Gentle in Action

At the same time as signs of ageing decreased, the serum also calmed the skin, with red areas and blemishes decreasing significantly. Clinical testing on volunteers with self-diagnosed sensitive skin showed so little reaction that this serum has also been approved for use on sensitive skin.

    Our Ingredients

    We focus on locally sourced Mediterranean ingredients, many of which come from our Organic Farm in Sicily. Each ingredient must smell and feel amazing but more importantly have clear benefits in use, without any compromise in skin kindness.

  • 70% APM (Alpine Plant Melatonin)

    Hormones can have a wide variety of profound effects on the skin. Oestrogen, progesterone and the androgens have for example been shown to regulate the condition of the skin via multiple mechanisms that can address skin degradation, wrinkles and dryness, and stimulate the development of new skin cells. Phytomelatonin has been shown to have very similar effects in laboratory trials.

    Dr. Ferri's Alpine Plant Melatonin (APM), a patented Phytomelatonin extract, has been used in this serum at 70%. As a result, the Phytomelatonin Rejuvenating Serum has been shown in independent clinical trials to visibly reduce signs of skin ageing, while even calming and soothing the skin.

  • 30% Vitamin E

    A stable form of Vitamin E with antioxidant properties. It strengthens the skin barrier function and has moisturising benefits.

  • Full Ingredients

    Avena Sativa (Oat) Kernel Extract*, Tocopheryl Acetate, Achillea
    Millefolium Flower Extract*, Salvia Officinalis (Sage) Leaf Extract*.

    *Dr. Ferri's patented technique has extracted a lipophilic
    phytomelatonin oil from these three alpine plants.

  • Free From

    The Phytomelatonin Rejuvenating Serum is free from parabens, artificial preservatives, phthalates, silicones, fragrance, SLS, SLES, silicones, petrochemicals, TEA, DEA, artificial colours, essential oils, animal-derived ingredients, palm oil and unsustainably sourced palm oil derivatives. 

Research Shows Phytomelatonin Promotes Skin Vitality & COUNTERACTS SIGNS OF AGEING

A major finding in Dr. Ferri's work with her colleagues at the University of Calabria, published in 2019, was that Phytomelatonin can triple the vitality of skin cells in the laboratory. Beyond this increase in cell viability, the research team also observed that Phytomelatonin can promote cellular changes that occur in the course of skin regeneration.

“It’s only our knowledge of the science of skincare that makes it possible to design products that are so highly effective whilst being so gentle on the skin.”

Dr. Francesca Ferri
“The Phytomelatonin Rejuvenating Serum is truly the work of a lifetime by our incredible Scientific Director. Since I learnt about her research into Phytomelatonin and the patented extraction process, I knew that we had the opportunity to develop a game-changing anti-ageing product. It’s such a magical ingredient. But I needed to confirm just how effective the serum is through clinical trials. I was amazed to discover that it not only reduced signs of visible ageing, but also calmed and soothed the skin”

Irene Forte